HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Benzylcyclohexan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | 1-Cyclohexylpyrrolidine | HCID 139064 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Benzylcyclohexan-1-one | HCID 98945 | — |
Reaction Steps
A mixture of 1-(1-pyrrolidinyl)cyclohexane (85.4 g) and benzyl chloride (100 ml) in dioxane (400 ml) was heated under reflux for 23 hours under nitrogen. Water (100 ml) was then added and the brown oil was distilled to give (2RS)-2-phenylmethylcyclohexanone (47.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05057513 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-21da1710588a4bcabd47799acedec4b2 |
| Source note | uspto-grants-1991_10 |