HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 14850773, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | HCID 14850772 | HCID 14850772 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14850773 | HCID 14850773 | — |
Reaction Steps
A solution of 5.9 g of 4-(diethylphosphonomethyl)-2-cyanoquinoline in 24 ml of concentrated sulfuric acid is heated at 80° for 5 minutes, cooled to 0° and added slowly to an ice-cooled mixture of 50 g of sodium carbonate in 50 ml of water and 100 ml of methylene chloride. The organic layer is separated, dried over sodium sulfate and evaporated to dryness to yield 4-(diethylphosphonomethyl)-quinoline-2-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05057506 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-9f2c55ce28684f51a2831111e7414d04 |
| Source note | uspto-grants-1991_10 |