1-Bromo-4-(trimethoxymethyl)benzene → HCID 15021999, compound

HRID 345378Notes

Reaction equation

HRID 345378 reaction equation
[OH:1][CH2:2][C:3]([CH2:9][OH:10])([CH2:6][CH2:7][CH3:8])[CH2:4][SH:5].CO[C:13](OC)(OC)[C:14]1[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][CH:15]=1>>[Br:20][C:17]1[CH:18]=[CH:19][C:14]([C:13]23[S:5][CH2:4][C:3]([CH2:6][CH2:7][CH3:8])([CH2:9][O:10]2)[CH2:2][O:1]3)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 135812791-Bromo-4-(trimethoxymethyl)benzeneHCID 15021997HCID 15021997, compound

Product 1

HCID 15021999HCID 15021999, compound

Procedure

Using a method analogous to that described in stage iv of Example 5 2,2-di-hydroxymethyl-pentan-1-thiol and trimethyl 4-bromo-orthobenzoate were reacted together to give 1-(4-bromophenyl)-4-n-propyl-2,6-dioxa-7-thiabicyclo[2,2,2]octane (colourless solid).

Workup

  1. customwere reacted together

Sources & evidence

ORD record
ord-303d6cf4c40f45dc970bdb491660bef8
Source dataset
uspto-grants-1991_10
Patent number
US05057508

Reaction notes

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