Potassium Nitrate → HCID 178481719, compound

HRID 345384Notes

Reaction equation

HRID 345384 reaction equation
[N+:1]([O-:4])([O-])=[O:2].[K+].[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:13]3=[N:18][N:19]([CH3:21])[N:20]=[C:12]3[CH:11]=[CH:10][C:9]=2[N:8]=1>>[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:13]3=[N:18][N:19]([CH3:21])[N:20]=[C:12]3[C:11]([N+:1]([O-:4])=[O:2])=[CH:10][C:9]=2[N:8]=1

Participants

3

Reactant 2

HCID 24434Potassium NitrateHCID 178481712HCID 178481712, compound

Product 1

HCID 178481719HCID 178481719, compoundYield 22.4%

Conditions

Temperature
0 °C

Procedure

Finely powdered potassium nitrate (0.47 g, 4.6 mmol) was added to an ice-cooled solution of 7,8-dihydroxy-2-methyl-2H-1,2,3-triazolo[4,5-f]quinoxaline (1.0 g, 4.6 mmol). The mixture was stirred at 0° C. for 11/2 h, then at room temperature for 4 h and finally poured into ice/water. The resulting solution was extracted with ethyl acetate. The extract was dried over anhydrous sodium sulfate and concentrated to dryness giving 0.27 g (22%) of the nitro compound; m.p.>300° C.; IR (KBr): 1700 cm-1 ; 1H-NMR (DMSO-d6): 4.63 (s, 3H, CH3), 8.15 (s, 1H, ArH), 12.1 (broad s, 1H, OH), 13.0 (broad s, 1H, OH).

Workup

  1. waitat room temperature for 4 h
  2. extractionThe resulting solution was extracted with ethyl acetate
  3. dry with materialThe extract was dried over anhydrous sodium sulfate
  4. concentrationconcentrated to dryness

Sources & evidence

ORD record
ord-322addac198c43e5a5fae472879d94ae
Source dataset
uspto-grants-1991_10
Patent number
US05057516

Reaction notes

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