Potassium Nitrate → HCID 178526418, compound

HRID 345388Notes

Reaction equation

HRID 345388 reaction equation
[N+:1]([O-:4])([O-])=[O:2].[K+].[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][CH:11]=[C:12]3[N:20]=[CH:19][S:18][C:13]3=2)[N:8]=1>S(=O)(=O)(O)O>[OH:6][C:7]1[C:16]([OH:17])=[N:15][C:14]2[C:9](=[CH:10][C:11]([N+:1]([O-:4])=[O:2])=[C:12]3[N:20]=[CH:19][S:18][C:13]3=2)[N:8]=1

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 178517010HCID 178517010, compound

Product 1

HCID 178526418HCID 178526418, compoundYield 63.1%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Finely powdered potassium nitrate (92 mg, 0.9 mmol) was added to a stirred and ice-cooled solution of 7,8-dihydroxythiazolo[5,4-f]quinoxaline (0.20 g, 0.9 mmol) in 5 ml of conc. sulfuric acid. The mixture was stirred at 0° C. for 30 min, then at room temperature for 4 h, and finally poured into ice/water. The resulting precipitate was isolated by filtration, washed with water, and dried giving 0.15 g (62%) of the nitro compound; m.p.>360° C., IR (KBr) 1680 cm-1 ; 1H-NMR (DMSO-d6) 8.06 (s, 1H, ArH), 9.53 (s, 1H, ArH), 12.23 (broad s, 1H, OH), 12.76 (broad s, 1H, OH).

Workup

  1. stirringThe mixture was stirred at 0° C. for 30 min
  2. customThe resulting precipitate was isolated by filtration
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-86b4246ee82f41e8a4ec05d6d3735fef
Source dataset
uspto-grants-1991_10
Patent number
US05057516

Reaction notes

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