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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34540Generated: October 25, 2026

1-Adamantanol → 1-Adamantyl 2-(p-nitrophenyl)propionate

https://huagongshe.com/reaction/34540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AdamantanolHCID 64152—
Reactant2-(4-Nitrophenyl)propionic acidHCID 89244—
Reactant1-Methylcyclohexyl 2-(p-nitrophenyl)propionateHCID 54068492—
Product1-Adamantyl 2-(p-nitrophenyl)propionateHCID 2129816792%

Reaction Steps

Using a method similar to that used in the preparation of 1-methylcyclohexyl 2-(p-nitrophenyl)propionate, 14.6 g of 2-(p-nitrophenyl)propionic acid, but using 1-adamantol instead of 1-methylcyclohexanol, were reacted to obtain 22.74 g (92% yield) of 1-adamantyl 2-(p-nitrophenyl)propionate as a light yellow viscous liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04762840
Source datasetuspto-grants-1988_08
ORD IDord-c5b67b715fb843d8baa6939c205a5268
Source noteuspto-grants-1988_08