1-Methylcyclohexyl 2-(p-aminophenyl)-propionate → 1-Adamantyl 2-(p-aminophenyl)propionate

HRID 34541Notes

Reaction equation

HRID 34541 reaction equation
NC1C=CC(C(C)C(OC2(C)CCCCC2)=O)=CC=1.[N+:20]([C:23]1[CH:28]=[CH:27][C:26]([CH:29]([CH3:43])[C:30]([O:32][C:33]23[CH2:42][CH:37]4[CH2:38][CH:39]([CH2:41][CH:35]([CH2:36]4)[CH2:34]2)[CH2:40]3)=[O:31])=[CH:25][CH:24]=1)([O-])=O>>[NH2:20][C:23]1[CH:24]=[CH:25][C:26]([CH:29]([CH3:43])[C:30]([O:32][C:33]23[CH2:42][CH:37]4[CH2:38][CH:39]([CH2:41][CH:35]([CH2:36]4)[CH2:34]2)[CH2:40]3)=[O:31])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 137540711-Methylcyclohexyl 2-(p-aminophenyl)-propionateHCID 212981671-Adamantyl 2-(p-nitrophenyl)propionate

Product 1

HCID 212981731-Adamantyl 2-(p-aminophenyl)propionateYield 100%

Procedure

Using a method similar to that used in the preparation of 1-methylcyclohexyl 2-(p-aminophenyl)-propionate, 21.4 g of 1-adamantyl 2-(p-nitrophenyl)propionate were reacted to obtain 19.42 g (100% yield) of 1-adamantyl 2-(p-aminophenyl)propionate of a light yellow viscous liquid.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-7128870d458547f4ab41ea21bae4d085
Source dataset
uspto-grants-1988_08
Patent number
US04762840

Reaction notes

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