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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345625Generated: October 31, 2026

Aminoacetaldehyde dimethyl acetal → HCID 19778271, compound

https://huagongshe.com/reaction/345625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminoacetaldehyde dimethyl acetalHCID 89728—
Reactant2-IsothiocyanatothiopheneHCID 12348170—
SolventTolueneHCID 1140—
ProductHCID 19778271HCID 19778271—

Reaction Steps

A mixture of 2-isothiocyanatothiophene (16.9 g, 0.12 mol) and aminoacetaldehyde dimethyl acetal (12.6 g, 0.12 mol) in 200 ml toluene is refluxed for 2 hours. After removal of the toluene, the residue is dissolved in 200 ml ethanol and 45 ml conc. HCl added. After the reaction is refluxed for 5 hours, it is poured onto ice. The product is collected and purified by recrystallization.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05057613
Source datasetuspto-grants-1991_10
ORD IDord-f72cb119bd0b443f89adcbbcca94b55f
Source noteuspto-grants-1991_10