Chloroacetaldehyde → HCID 13958033, compound

HRID 345643Notes

Reaction equation

HRID 345643 reaction equation
[Cl:1][CH2:2][CH:3]=O.[CH2:5]([NH2:12])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>O>[Cl:1][CH2:2][CH:3]=[N:12][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 33ChloroacetaldehydeHCID 7504Benzylamine

Product 1

HCID 13958033HCID 13958033, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A solution of 4 ml of chloroacetaldehyde in 20 ml of demineralized water was cooled and a solution of 2.14 g of benzylamine in 10 ml of water was added thereto with stirring. After stirring for 5 minutes at 10° to 15° C., a gum was obtained and a turbid solution which was extracted with 30 ml and then with 20 ml of benzene. The organic solution was dried, filtered, rinsed and the filtrate was evaporated to dryness under vacuum to obtain 3.34 g of 2-chloro-N-benzylethanimine which was used as is for the next step.

Workup

  1. stirringAfter stirring for 5 minutes at 10° to 15° C.
  2. customa gum was obtained
  3. extractiona turbid solution which was extracted with 30 ml
  4. customThe organic solution was dried
  5. filtrationfiltered
  6. washrinsed
  7. customthe filtrate was evaporated to dryness under vacuum

Sources & evidence

ORD record
ord-ee0774f84ac14914a3a8400aac5ea838
Source dataset
uspto-grants-1991_10
Patent number
US05057512

Reaction notes

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