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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345671Generated: October 29, 2026

Dimethylformamide → HCID 18780224, compound

https://huagongshe.com/reaction/345671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantHCID 18780217HCID 18780217—
SolventAmmoniaHCID 222—
ProductHCID 18780224HCID 18780224—

Reaction Steps

A solution of 2.50 g of 3-[1-(3-azidopropyl)-3-indolyl]-4-(1-methyl-3-indolyl)furan-2,5-dione in 13 ml of DMF and 18 ml of 33% aqueous ammonia was heated to 140° C. for 4 hours. The product was filtered off from the cooled mixture to give 2.27 g of 3-[1-(3-azidopropyl)-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione, m.p. 222°-224° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05057614
Source datasetuspto-grants-1991_10
ORD IDord-3e591cf09dae4b68ad1435f81f574031
Source noteuspto-grants-1991_10