Chloride → HCID 11086987, compound

Participants

Reaction Steps

A solution of 3.7 mmol of N-(p-nitrobenzyl)-benzamide in thionyl chloride was refluxed under an inert atmosphere for 30 minutes and after cooling, the excess thionyl chloride was removed under vacuum to leave a solid residue. The residue was crystallized from dry cyclohexane under dry nitrogen (Note: the subsequent filtration had to be done under dry nitrogen also to obtain an 85% yield of the purified imidoyl--chloride melting at 71° to 73° C. (Lit. m.pt. 73--4 Huisgen et al--Loc. cit) which was used directly in the next step.

Provenance & Evidence