HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → trans-1-Benzyl-4-hydroxy-3-(2-hydroxyethyl-methylamino)-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-Methylaminoethanol | HCID 5247031 | — |
| Reactant | 3-Benzyl-6-oxa-3-azabicyclo(3.1.0)hexane | HCID 9815370 | — |
| Product | trans-1-Benzyl-4-hydroxy-3-(2-hydroxyethyl-methylamino)-pyrrolidine | HCID 15069974 | — |
Reaction Steps
17.5 g (0.1 mol) of 3-benzyl-6-oxa-3-azabicyclo[3.1.0]hexane are reacted with 17 g (0.1 mol) of methylaminoethanol in 200 ml of water analogously to Example D a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05059597 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-ebc3dc9f5ff24b6a81296a5a573e8718 |
| Source note | uspto-grants-1991_10 |