6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine → Octahydro-1H-pyrrolo[3,4-b]pyridine

Participants

Reaction Steps

69 g (0.32 mol) of 6-benzyl-octahydropyrrolo[3,4-b]pyridine are hydrogenated in 450 ml of methanol over 7 g of palladium-on-active charcoal (5% strength) at 90° C./90 bar in the course of 3 hours. The catalyst is then filtered off, the filtrate is concentrated and the residue is distilled. 33.8 g (84% of theory) of a colorless solid having a melting point of 65°-67° C. and a boiling point of 78° C./9 mbar are obtained.

Provenance & Evidence