HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2,4-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2,4-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane-7-carboxylate | HCID 15070019 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,4-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane | HCID 15070020 | — |
Reaction Steps
13.2 g (61.6 mmol) of ethyl 2,4-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane-7-carboxylate are heated under reflux with 39 g of Ba(OH)2.8H2O in 200 ml of water overnight. K2CO3 is added, the BaCO3 is filtered off with suction and the filtrate is extracted several times with CHCl3. The extract is dried over K2CO3 and concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05059597 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-7a923630bc034f229a0dcec310031ff0 |
| Source note | uspto-grants-1991_10 |