HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 1-Phenyl-3,4-dihydroisoquinoline | HCID 609926 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide | HCID 10809638 | — |
Reaction Steps
The mixture of 1-phenyl-3,4-dihydroisoquinoline (292.0 g) and benzyl bromide (176 ml) in acetonitrile (3 l) was refluxed for 1 hour. After cooling the mixture to room temperature, the solvent was evaporated in vacuo. The residue was triturated with diethyl ether (1 l) to give 1-phenyl-2-benzyl-3,4-dihydroisoquinolinium bromide (471.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05059608 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-d03d24d666134bcbb7e9887a3efdf6d4 |
| Source note | uspto-grants-1991_10 |