Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 345922Generated: October 31, 2026

Sodium Hydroxide → HCID 14774142, compound

https://huagongshe.com/reaction/345922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 10296250HCID 10296250—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
ProductHCID 14774142HCID 14774142—

Reaction Conditions

Temperature60 °C

Reaction Steps

A mixture of 2.6 g of methyl 3-methoxy-4-[3-(2-quinolinylmethyloxy)benzyloxy]benzoate and 0.6 g of NaOH in 15 ml of THF and 2 ml of H2O are heated at 60° C. overnight. The reaction mixture is diluted with 20 ml of HO and acidified to pH 4. The product is collected on a filter and dried to give 3-methoxy-4-(3-(2-quinolinylmethyloxy)benzyloxy)benzoic acid. (M.P. 188°-190° C.)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05059610
Source datasetuspto-grants-1991_10
ORD IDord-1c918cc290c34801b99ef24fe0ca78bd
Source noteuspto-grants-1991_10