Dimethylformamide dimethyl acetal → N-((Dimethylamino)methylene)-7-phenylpyrazolo(1,5-a)pyrimidine-3-carboxamid

Participants

Reaction Steps

A mixture of 600 mg of 7-phenylpyrazolo(1,5-a)pyrimidine-3-carboxamide (Example 7), 5.0 ml of N,N-dimethylformamide dimethyl acetal and 25.0 ml of dichloromethane are heated on a steam bath for 2 hours with complete solution taking place. The solution is evaporated in vacuo to give a solid. The solid is then recrystallized from acetone to give 58 mg of the desired product as yellow needles, mp 198°-201.5° C.

Provenance & Evidence