反应详情

15 g (36.4 mmol) of the product from Example 18 are heated to 120° for 3 hours together with 30 ml of octylamine. After cooling, 40 ml of water are added and the mixture is extracted three times using 30 ml of methylene chloride. The CH2Cl2 solution is washed with water, dried over Na2SO4 and evaporated. The oily residue is dissolved in hexane/acetone and purified chromatographically on an SiO2 column. The main fraction is a viscous material.

1. temperatureAfter cooling
2. extractionthe mixture is extracted three times
3. washThe CH2Cl2 solution is washed with water
4. dry with materialdried over Na2SO4
5. customevaporated
6. dissolutionThe oily residue is dissolved in hexane/acetone
7. custompurified chromatographically on an SiO2 column