Isopropanol → HCID 19991773, compound

Participants

Reaction Steps

12.5 g of 2-chloro-4-isopropyloxy-6-(2,2,6,6-tetramethylpiperidin-1-yl)- 1,3,5-triazine (product from Example 55), 11.2 g of finely pulverized potassium hydroxide and 0.7 g of tetrabutylammonium hydrogen sulfate are initially introduced in 60 ml of toluene. 2.6 g of isopropanol are added dropwise during the course of 15 minutes to this orange-colored suspension: weakly exothermic reaction to about 30+. The pale brown contents of the flask are stirred at 60° for 8 hours, cooled to 0°-5°, and diluted with 80 ml of water and then with 40 ml of toluene. The brown, aqueous phase is separated off from the colorless, organic phase and the latter is washed four times, each with 80 ml of water, dried over sodium sulfate and completely evaporated in vacuo. A weakly yellowish oil is obtained which solidifies after a short time to give 2,4-bis-isopropyloxy-6-(2,2,6,6-tetramethylpiperidin-1-yl)-1,3,5-triazine with a melting range of 70°-98°.

Provenance & Evidence