HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Chloromethyl)quinoline → 7-Methyl-3-[(quinolin-2-yl)methoxy]-7,8-dihydroquinolin-5(6H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Chloromethyl)quinoline | HCID 20394 | — |
| Reactant | 123094-71-3 | HCID 14422734 | — |
| Product | 7-Methyl-3-[(quinolin-2-yl)methoxy]-7,8-dihydroquinolin-5(6H)-one | HCID 14422735 | 67% |
Reaction Steps
By the method of Example 55, 7,8-dihydro-3-hydroxy-7-methyl-5(6H)-quinolone and 2-chloromethylquinoline were converted to present title product in 67% yield, m.p. 141°-144° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05059609 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-325b9136787a4b53a226d7df6f586027 |
| Source note | uspto-grants-1991_10 |