Methyl 3-Hydroxybenzoate → HCID 19600740, compound

HRID 346039Notes

Reaction equation

HRID 346039 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[O:15][CH2:14][CH:13](Br)[C:12]2=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:21][C:22]1[CH:23]=[C:24]([CH:29]=[CH:30][CH:31]=1)[C:25]([O:27][CH3:28])=[O:26]>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[O:15][CH2:14][CH:13]([O:21][C:22]1[CH:31]=[CH:30][CH:29]=[C:24]([C:25]([O:27][CH3:28])=[O:26])[CH:23]=1)[C:12]2=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 88068Methyl 3-HydroxybenzoateHCID 19600716HCID 19600716, compound

Product 1

HCID 19600740HCID 19600740, compound

Procedure

By the method of Example 72, 6-benzyloxy-3-bromo-4-chromanone (49.9 g, 0.15 mol) and methyl 3-hydroxybenzoate (22.8 g, 0.15 mol) were converted to present title product purified by chromatography on silica gel using CH2Cl2 as eluant, 2.19 g; tlc Rf 0.22 (CH2Cl2).

Sources & evidence

ORD record
ord-7199ae4af3b8426a839a7e7c5a4f3869
Source dataset
uspto-grants-1991_10
Patent number
US05059609

Reaction notes

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