Sulfuric Acid → HCID 131717044, compound

HRID 346076Notes

Reaction equation

HRID 346076 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][N:5]([CH3:10])[C:6]=1[N+:7]([O-])=[O:8].[S:11](=[O:15])(=[O:14])([OH:13])[OH:12]>CO.[Pd]>[OH2:8].[S:11]([O-:15])([OH:14])(=[O:13])=[O:12].[NH2:1][C:2]1[C:6]([NH2:7])=[N+:5]([CH3:10])[NH:4][CH:3]=1

Participants

5

Reactant 2

HCID 1118Sulfuric AcidHCID 5883331H-Pyrazol-4-amine, 1-methyl-5-nitro-

Product 1

HCID 131717044HCID 131717044, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

200 mg (1.41 mmoles) of 4-amino-1-methyl-5-nitropyrazol are hydrated in 50 ml absolute methanol with catalytic quantities of palladium/carbon at room temperature and 30 bar. The hydration is terminated at 17 hours. A colorless precipitate is precipitated out of the filtrated solution when adding 135 mg (1.41 mmoles) of concentrated sulfuric acid, which precipitate is removed by suction and recrystallized from water.

Workup

  1. customThe hydration is terminated at 17 hours
  2. customA colorless precipitate is precipitated out of the filtrated solution when
  3. customprecipitate
  4. customis removed by suction
  5. customrecrystallized from water

Sources & evidence

ORD record
ord-931fcbfa664e43b1a79c4f6f35836439
Source dataset
uspto-grants-1991_10
Patent number
US05061289

Reaction notes

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