HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → 1,1-Dimethoxycyclohexane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,1-Dimethoxycyclohexane | HCID 13616 | — |
Reaction Steps
A mixture of cyclohexanone (52 ml, 0.5 mol), trimethylorthoformate (66 ml, 0.6 mol), methanol (51 ml, 1.26 mol) and concentrated H2SO4 (1 drop) was refluxed for 18 hours. A solution sodium methoxide in methanol was added until the mi was neutral, and the mixture was fractionally distilled. 1,1-Dimethoxycyclohexane was obtained from the fraction b.p. 162°-164° C. (50.6 g, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05061626 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-8d809266f66b474db9ff18eb07c694bf |
| Source note | uspto-grants-1991_10 |