Nitric Acid → HCID 67718416, compound

HRID 346127Notes

Reaction equation

HRID 346127 reaction equation
[C:1]([NH:8][C:9]1[CH:16]=[CH:15][C:12]([C:13]#[N:14])=[CH:11][CH:10]=1)([C:3]([O:5][CH2:6][CH3:7])=[O:4])=[O:2].C(OC(=O)C)(=O)C.[N+:24]([O-])([OH:26])=[O:25]>C(O)(=O)C>[C:1]([NH:8][C:9]1[CH:10]=[CH:11][C:12]([C:13]#[N:14])=[CH:15][C:16]=1[N+:24]([O-:26])=[O:25])([C:3]([O:5][CH2:6][CH3:7])=[O:4])=[O:2]

Participants

5

Reactant 3

HCID 944Nitric Acid2×HCID 7918Acetic AnhydrideHCID 2264007HCID 2264007, compound

Product 1

HCID 67718416HCID 67718416, compoundYield 81%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Procedure

To a mixture of 1.0 g (4.0 mmol) 4-ethoxalylaminobenzonitril in 4 ml glacial acetic acid was added 4 ml acetic anhydride. At 0° C. a solution of 1 ml 100% nitric acid in 2 ml glacial acetic acid was added dropwise, and after 15 min. further 1 ml 100% nitric acid was added. Stirring was continued at 0° C. for 1 h. The reaction mixture was poured into 50 ml ice-water to give 0.95 g (81%) of 4-ethoxalylamino-3-nitrobenzonitril. M.p. 151.8° C.

Sources & evidence

ORD record
ord-3b5dd7b34a46476f8334f242f9617948
Source dataset
uspto-grants-1991_10
Patent number
US05061706

Reaction notes

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