HCID 19990428, compound → HCID 19990468, compound

Participants

Reaction Steps

A solution of 3-ethoxalylamino-2-nitrobenzotrifluoride (0.28 g, 0.9 mmol) in 30 ml of 96% ethanol was hydrogenated at atmospheric pressure and room temperature in the presence of 28 mg of 5% platinum on carbon for 5 min. The catalyst was removed by filtration, and the filtrate was evaporated to dryness. The residue was triturated with ether to give 77 mg 34%) of the title compound. M.p. 150° C. dec. 1H-NMR (DMSO-d6): 7.20-7.67 (m, 3H, ArH), appr. 12 (very broad s, 1H, NH); IR (KBr): 1700 cm-1 ; MS (m/e): 246 (28%, M+).

Provenance & Evidence