Methanol → HCID 23168169, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.5 g (2.1 mmol) 7-carboxymethyl-1-hydroxyquinoxaline-2,3(1H,4H)-dione, 5 dr. sulfuric acid (97%) and 50 ml methanol was refluxed for 1 h. After cooling to 25° C. the precipitate was filtered off and washed with ether to give 0.4 g (76%) of 1-hydroxy-7-methoxycarbonylmethyl-quinoxaline-2,3(1H,4H)-dione. M.p. decomp. 1H-NMR (DMSO-d6): 12.2 (1H, broad s), 7.5-7.1 (3H, m), 3.9 (2H, s), 3.7 (3H,s).

Provenance & Evidence