HCID 67833120, compound → HCID 19990437, compound

Participants

Reaction Steps

A solution of 0.5 g (1.9 mmol) 3-ethoxalylamino-4-nitrobenzonitril in 50 ml ethanol was hydrogenated at atm. pressure by using 25 mg 5% Pt-C as a catalyst. The catalyst was filtered off, and the filtrate was evaporated in vacuo. Cyclization was achieved by evaporation with acetic acid. Recrystallization (dimethylformamide-water) gave 0.25 g (65%) of 6-cyano-1-hydroxyquinoxaline-2,3(1H,4H)-dione. M.p. 250° C. decomp. 1H-NMR (DMSO-d6) 7.53 (s) and 7.40 (s)--a total of 3H.

Provenance & Evidence