Ethanol → HCID 13500736, compound

Participants

Reaction Steps

Add thionyl chloride (2.0 ml) to absolute ethanol (25 ml) at 0°-5°. To this solution add S-phenethyl-L-cysteine (2.5 g, 1.11 mmole). Warm the resulting mixture to room temperature, and then heat at 60° for 5 hours. Concentrate the reaction mixture in vacuo, dissolve the resultant residue in dichloromethane (CH2Cl2), and concentrate the solution in vacuo. Dissolve the residue in absolute ethanol, treat with DARCO, filter and concentrate in vacuo to give the title compound, a white solid (2.90 g) m.p. 155°-156°, [α]D26 =-1.5° (MeOH).

Provenance & Evidence