Sodium Hydroxide → HCID 10426604, compound

HRID 346185Notes

Reaction equation

HRID 346185 reaction equation
C[O:2][C:3](=[O:25])[C@H:4]([CH2:21][CH2:22][S:23][CH3:24])[NH:5][C:6](=[O:20])[CH:7]([CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH2:8][S:9]C(=O)C.[OH-].[Na+]>CO>[SH:9][CH2:8][CH:7]([CH2:13][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:6]([NH:5][C@H:4]([C:3]([OH:25])=[O:2])[CH2:21][CH2:22][S:23][CH3:24])=[O:20]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 10045512HCID 10045512, compound

Product 1

HCID 10426604HCID 10426604, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Dissolve the product of Step 1 in methanol (20 ml) and treat with 1N NaOH (20.4 ml) as described in Example 1, Step 2 to give the title compound, a white solid, m.p. 132°-135°, [α]D26 =-34.6° (MeOH).

Sources & evidence

ORD record
ord-f39b2e1858d04a7c9c6ea5e528d05ecf
Source dataset
uspto-grants-1991_10
Patent number
US05061710

Reaction notes

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