Thiazolidinedione → 5-[4-(2-(4-Chlorophenyl)ethylthio)phenylmethylene]thiazolidine-2,4-dione

HRID 346193Notes

Reaction equation

HRID 346193 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][S:10][C:11]2[CH:18]=[CH:17][C:14]([CH:15]=O)=[CH:13][CH:12]=2)=[CH:4][CH:3]=1.[S:19]1[CH2:23][C:22](=[O:24])[NH:21][C:20]1=[O:25]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][S:10][C:11]2[CH:18]=[CH:17][C:14]([CH:15]=[C:23]3[S:19][C:20](=[O:25])[NH:21][C:22]3=[O:24])=[CH:13][CH:12]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 144599684-[2-(4-Chlorophenyl)ethylthio]benzaldehyde

Product 1

HCID 539456615-[4-(2-(4-Chlorophenyl)ethylthio)phenylmethylene]thiazolidine-2,4-dione

Procedure

4-[2-(4-Chlorophenyl)ethylthio]benzaldehyde and thiazolidine-2,4-dione were coupled according to the method of Example 5 to form present title product in similar yield; m.p. 215°-225° C.

Sources & evidence

ORD record
ord-2a5dc4b4c0234643aa46179dc2709624
Source dataset
uspto-grants-1991_10
Patent number
US05061717

Reaction notes

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