2-Mercaptomethyl-3-methylbutan-1-ol → 2-(4-Ethynylcyclohexyl)-5-isopropyl-1,3-oxathiane

HRID 346259Notes

Reaction equation

HRID 346259 reaction equation
[C:1]([CH:3]1[CH2:8][CH2:7][CH:6]([CH:9]=[O:10])[CH2:5][CH2:4]1)#[CH:2].[SH:11][CH2:12][CH:13]([CH:16]([CH3:18])[CH3:17])[CH2:14]O>>[C:1]([CH:3]1[CH2:8][CH2:7][CH:6]([CH:9]2[S:11][CH2:12][CH:13]([CH:16]([CH3:18])[CH3:17])[CH2:14][O:10]2)[CH2:5][CH2:4]1)#[CH:2]

Participants

3

Reactant 2

HCID 133532852-Mercaptomethyl-3-methylbutan-1-olHCID 224210104-Ethynylcyclohexane-1-carbaldehyde

Product 1

HCID 199906392-(4-Ethynylcyclohexyl)-5-isopropyl-1,3-oxathiane

Procedure

Using the method described in Example 1(v) and starting from 4-ethynyl cyclohexanecarboxaldehyde (European Patent Application No. 88305107) and 2-mercaptomethyl-3-methylbutan-1-ol, 2-(4-ethynylcyclohexyl)-5-isopropyl-1,3-oxathiane was obtained as a mixture of isomers.

Sources & evidence

ORD record
ord-b4e10952b52c4cbc8568c599e86f2051
Source dataset
uspto-grants-1991_10
Patent number
US05061726

Reaction notes

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