HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl 5-hydroxy-7-(2-methylphenyl)-1-oxo-1,3,4,7-tetrahydrobenzo[c]furan-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 13577749 | HCID 13577749 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethyl 5-hydroxy-7-(2-methylphenyl)-1-oxo-1,3,4,7-tetrahydrobenzo[c]furan-6-carboxylate | HCID 54699091 | — |
Reaction Steps
10 mmol of ethyl 7-(2-methylphenyl)-5-methylamino-1-oxo-1,3,4,7-tetrahydrobenzo[c]furan-6-carboxylate are dissolved in 50 mmol of THF, 3 ml of concentrated HCl and 5 ml of water are added, and the mixture is boiled for 1 hour and then concentrated. The substance is identical to that from Example 3a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04762853 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-c6bfb43ff2ed4d24a28bd74574555bab |
| Source note | uspto-grants-1988_08 |