HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 6-Methoxy-2-naphthylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | Chloroform methanol water | HCID 21866399 | — |
| Product | 6-Methoxy-2-naphthylacetic acid | HCID 32176 | — |
Reaction Steps
The final products, i.e. the phospholipid-drug conjugates obtained at the end of step 6, were subjected to TLC analysis under the following conditions: Silica gel 60 on aluminum sheet. Eluent is chloroform:methanol:water (65:35:5 v/v). Indicator is a spray of the composition: 4-methoxybenzaldehyde (10 ml), absolute ethanol (200 ml), 98% sulfuric acid (10 ml) and glacial acetic acid (2 ml). The chromatogram is sprayed with the indicator and then charred at 100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07173018B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-ebb8d678259740259b882bd91435c301 |
| Source note | uspto-grants-2007_02 |