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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 346445Generated: October 25, 2026

Acetic Acid → 6-Methoxy-2-naphthylacetic acid

https://huagongshe.com/reaction/346445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantEthanolHCID 702—
ReactantSulfuric AcidHCID 1118—
Reactant4-MethoxybenzaldehydeHCID 31244—
ReactantChloroform methanol waterHCID 21866399—
Product6-Methoxy-2-naphthylacetic acidHCID 32176—

Reaction Steps

The final products, i.e. the phospholipid-drug conjugates obtained at the end of step 6, were subjected to TLC analysis under the following conditions: Silica gel 60 on aluminum sheet. Eluent is chloroform:methanol:water (65:35:5 v/v). Indicator is a spray of the composition: 4-methoxybenzaldehyde (10 ml), absolute ethanol (200 ml), 98% sulfuric acid (10 ml) and glacial acetic acid (2 ml). The chromatogram is sprayed with the indicator and then charred at 100° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173018B2
Source datasetuspto-grants-2007_02
ORD IDord-ebb8d678259740259b882bd91435c301
Source noteuspto-grants-2007_02