HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → BOC-L-methionyl-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Boc-L-methionine | HCID 89857 | — |
| Product | BOC-L-methionyl-pyrrolidine | HCID 11034003 | — |
Reaction Steps
2.50 g (10 mmol) BOC-methionine was coupled to 1.72 ml (20.6 mmol) pyrrolidine according to procedure B. Yield of crude product 3.38 g. The product was purified with a silica column using ethyl acetate as eluent. Yield 2.81 g (9.3 mmol, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07173024B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-b0b858eef19d47ada090bbefcb651833 |
| Source note | uspto-grants-2007_02 |