HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 11088437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Product | HCID 11088437 | HCID 11088437 | — |
Reaction Steps
2.65 g (10 mmol) BOC-L phenylalanine was coupled to 1.48 ml (17.8 mmol) pyrrolidine according to procedure B. Yield of active ester 3.22 g (8.9 mmol, 89%). Yield of crude product 3.33 g. The product was purified with a silica column using 1–2% methanol in dichloromethane as eluent. Yield 1.76 g (5.5 mmol, 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07173024B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-213fcc5d3d124d5a9115c7c650ac6d07 |
| Source note | uspto-grants-2007_02 |