o-Toluenesulfonyl chloride → HCID 10228032, compound

Participants

Reaction Steps

2-Methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and o-toluenesulfonylchloride (46 mg, 0.239 mmol) according to general method 3 to give before Boc-deprotection 160 mg of a purple solid. MS (posES-FIA) m/z=Found: 487.1; Calcd 487.14; 1H-NMR δ 7.74–7.16 (m, 8H), 6.78–6.52 (m, 4H), 3.27–3.16 (m, 8H), 2.58 (s, 3H).

Provenance & Evidence