2-Methoxy-4-methylbenzene-1-sulfonyl chloride → 2-Methoxy-4-methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide

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2-Methoxy-4-methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl] benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and 2-methoxy-4-methylbenzenesulfonylchloride (53 mg, 0.239 mmol) according to general method 3 to give 80 mg of a purple solid. MS (posES-FIA) m/z=Found: 517.2; Calcd 517.15; 1H NMR δ 7.67–7.37 (m, 6H), 7.10–7.04 (m, 2H), 6.97–6.74 (m, 2H), 6.30 (d, 1H), 4.06 (s, 3H), 3.26–3.09 (m, 8H), 2.37 (s, 3H).

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