Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34679Generated: October 27, 2026

Methyl iodide → 1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid

https://huagongshe.com/reaction/34679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 178524783HCID 178524783—
SolventMethanolHCID 887—
Product1-(3,5-Difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acidHCID 14769734—

Reaction Steps

Reaction of 1-(3,5-difluorobenzyl)-2-mercaptoimidazole-5-carboxylic acid prepared as in Example 1 with methyl iodide and sodium methoxide in methanol by standard techniques yields 1-(3,5-difluorobenzyl)-2-methylmercaptoimidazole-5-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04762850
Source datasetuspto-grants-1988_08
ORD IDord-4b16a3e593cb4118bc11307918d8d8ee
Source noteuspto-grants-1988_08