HRID346865

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21082210

未命名化合物

结构：CC1Cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2N1

HCID23346126

未命名化合物

结构：Cc1oc(C=Cc2ccccc2)nc1CN1c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2CC1C

HCID73741222

未命名化合物

PRODUCTS

生成物

结构：Cc1oc(Cc2ccccc2)nc1CN1c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2CC1C

HCID21082174

未命名化合物

PROCEDURE

实验过程

In analogy to example 75.2, from 1,1,1,3,3,3-hexafluoro-2-(2-methyl-2,3-dihydro-1H-indol-5-yl)-propan-2-ol (example 51.1) and 2-benzyl-4-chloromethyl-5-methyl-oxazole was prepared 1,1,1,3,3,3-hexafluoro-2-[2-methyl-1-(5-methyl-2-styryl-oxazol-4-ylmethyl)-2,3-dihydro-1H-indol-5-yl]-propan-2-ol, red oil, MS: 485 (MH+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a760968c8ff9468f9017f47aad07e039
来源数据集: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07173048B2
来源说明: uspto-grants-2007_02

反应 SMILES

[F:1][C:2]([F:20])([F:19])[C:3]([C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]([CH3:18])[CH2:12]2)([OH:8])[C:4]([F:7])([F:6])[F:5].[CH2:21]([C:28]1[O:29][C:30]([CH3:35])=[C:31]([CH2:33]Cl)[N:32]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.FC(F)(F)C(C1C=C2C(=CC=1)N(CC1N=C(C=CC3C=CC=CC=3)OC=1C)C(C)C2)(O)C(F)(F)F>>[CH2:21]([C:28]1[O:29][C:30]([CH3:35])=[C:31]([CH2:33][N:14]2[C:15]3[C:11](=[CH:10][C:9]([C:3]([OH:8])([C:2]([F:1])([F:19])[F:20])[C:4]([F:7])([F:6])[F:5])=[CH:17][CH:16]=3)[CH2:12][CH:13]2[CH3:18])[N:32]=1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1