反应详情

Sodium dithionite (174.11 g, 10 moles) in water (400 ml) was dropwise added to the nitrophenol ((a), 93.0 g, 0.38 mole) in refluxing ethanol. The resulting solution was refluxed for further 3 hours, then cooled at room temperature and filtered. The obtained solution was concentrated at a final volume of 100 ml; Water (100 ml) was added and the separated amine ((b), 72.0 g, 88%) was recovered as brown powder.

1. temperatureThe resulting solution was refluxed for further 3 hours
2. filtrationfiltered
3. concentrationThe obtained solution was concentrated at a final volume of 100 ml
4. additionWater (100 ml) was added
5. customthe separated amine ((b), 72.0 g, 88%) was recovered as brown powder