Azetidine → HCID 22313921, compound

HRID 347058Notes

Reaction equation

HRID 347058 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]3[CH:13]=[CH:14][C:15]([O:17][CH2:18][CH2:19][CH2:20]Br)=[CH:16][C:11]=3[S:10][N:9]=2)=[CH:4][CH:3]=1.[NH:22]1[CH2:25][CH2:24][CH2:23]1>>[N:22]1([CH2:20][CH2:19][CH2:18][O:17][C:15]2[CH:14]=[CH:13][C:12]3[C:8]([C:5]4[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=4)=[N:9][S:10][C:11]=3[CH:16]=2)[CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 10422AzetidineHCID 223140693-(4-Bromo-phenyl)-6-(3-bromo-propoxy)-benzo[d]isothiazole

Product 1

HCID 22313921HCID 22313921, compound

Procedure

According to the method in example 4, 3-(4-Bromo-phenyl)-6-(3-bromo-propoxy)-benzo[d]isothiazole and azetidine were converted to yield 6-(3-Azetidin-1-yl-propoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole, MS: 404 (MH+, 1Br).

Sources & evidence

ORD record
ord-e5577612135747d3a56c57f527097a40
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

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