Morpholine → HCID 22313933, compound

HRID 347061Notes

Reaction equation

HRID 347061 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:22]=[CH:21][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[NH:23]1[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[Br:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]2[C:10]3[CH:21]=[CH:22][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:23]4[CH2:28][CH2:27][O:26][CH2:25][CH2:24]4)=[CH:8][C:9]=3[S:13][N:12]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 22313931HCID 22313931, compound

Product 1

HCID 22313933HCID 22313933, compound

Procedure

According to the method in example 4, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and morpholine were converted to yield 3-(4-Bromo-phenyl)-6-(4-morpholin-4-yl-butoxy)-benzo[d]isothiazole, MS: 448 (MH+, 1Br).

Sources & evidence

ORD record
ord-dd9cddc9ca834138b354f82f9d5c9737
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

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