Azetidine → HCID 22314194, compound

HRID 347090Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:24]=[CH:23][C:10]2[C:11]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)=[N:12][S:13](=[O:15])(=[O:14])[C:9]=2[CH:8]=1.[NH:25]1[CH2:28][CH2:27][CH2:26]1>>[N:25]1([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:24]=[CH:23][C:10]3[C:11]([C:16]4[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=4)=[N:12][S:13](=[O:15])(=[O:14])[C:9]=3[CH:8]=2)[CH2:28][CH2:27][CH2:26]1

Participants

Reactant 2

HCID 10422Azetidine

HCID 22313958HCID 22313958, compound

Product 1

HCID 22314194HCID 22314194, compound

Procedure

According to the method in example 10, 6-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole 1,1-dioxide and Azetidine were converted to yield 6-(4-Azetidin-1-yl-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole 1,1-dioxide, MS: 405 (MH+, 1Cl).

Sources & evidence

ORD record: ord-94a48ff04e704bf7ad61f7e74a0f9a02
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07173043B2

Reaction notes

Loading…