3-Butyn-1-OL → HCID 22313907, compound

HRID 347098Notes

Reaction equation

HRID 347098 reaction equation
[F:1][C:2]([F:27])([F:26])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][C:16](OS(C(F)(F)F)(=O)=O)=[CH:17][C:12]=3[S:11][N:10]=2)=[CH:5][CH:4]=1.[CH2:28]([OH:32])[CH2:29][C:30]#[CH:31]>>[F:26][C:2]([F:27])([F:1])[C:3]1[CH:4]=[CH:5][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][C:16]([C:31]#[C:30][CH2:29][CH2:28][OH:32])=[CH:17][C:12]=3[S:11][N:10]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 135663-Butyn-1-OLHCID 57428077Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester

Product 1

HCID 22313907HCID 22313907, compound

Procedure

In analogy to example 14.1, Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester and 3-butyn-1-ol were converted to yield 4-[3-(4-Trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-but-3-yn-1-ol as orange semisolid, MS: 347 (M).

Sources & evidence

ORD record
ord-d0c64e8d13244e71a5dd773da6ae733a
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

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