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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347103Generated: October 29, 2026

Methanesulfonyl chloride → Methanesulfonic acid 3-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl ester

https://huagongshe.com/reaction/347103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
Reactant3-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-olHCID 22313930—
ProductMethanesulfonic acid 3-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl esterHCID 57428079—

Reaction Steps

In analogy to example 15.1, 3-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol and methane sulfonyl chloride were converted to yield Methanesulfonic acid 3-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-ynyl ester, which was directly subjected to the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173043B2
Source datasetuspto-grants-2007_02
ORD IDord-3e14322ddf034f819587cf8a180212b6
Source noteuspto-grants-2007_02