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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347138Generated: October 25, 2026

3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol → 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-ol

https://huagongshe.com/reaction/347138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-olHCID 22313906—
SolventDioxan ethanolHCID 22560076—
Product3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-olHCID 22314145—

Reaction Steps

In analogy to example 20.1, 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-prop-2-yn-1-ol in EtOH/dioxane was converted to yield 3-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-propan-1-ol as a brown oil, MS: 303 (M, 1Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07173043B2
Source datasetuspto-grants-2007_02
ORD IDord-f849d7dde63f4830b70bcd2bbbe50b9c
Source noteuspto-grants-2007_02