Dimethylamine → HCID 22314158, compound

HRID 347145Notes

Reaction equation

HRID 347145 reaction equation
[F:1][C:2]([F:28])([F:27])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][C:16]([CH2:18][CH2:19][CH2:20][CH2:21]OS(C)(=O)=O)=[CH:17][C:12]=3[S:11][N:10]=2)=[CH:5][CH:4]=1.[CH3:29][NH:30][CH3:31]>>[CH3:29][N:30]([CH3:31])[CH2:21][CH2:20][CH2:19][CH2:18][C:16]1[CH:15]=[CH:14][C:13]2[C:9]([C:6]3[CH:7]=[CH:8][C:3]([C:2]([F:28])([F:27])[F:1])=[CH:4][CH:5]=3)=[N:10][S:11][C:12]=2[CH:17]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 86585424HCID 86585424, compound

Product 1

HCID 22314158HCID 22314158, compound

Procedure

In analogy to example 17.1; Methanesulfonic acid 4-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-butyl ester and Dimethylamine were converted to yield Dimethyl-{4-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-amine as yellow oil, MS: 379 (MH+).

Sources & evidence

ORD record
ord-d6665d91ad794f34a264f43f87b6dde3
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

Loading…