HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Methoxyethyl)(methyl)amine → {3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-(2-methoxy-ethyl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Methoxyethyl)(methyl)amine | HCID 300977 | — |
| Reactant | 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene | HCID 22314034 | — |
| Product | {3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-(2-methoxy-ethyl)-methyl-amine | HCID 22314007 | — |
Reaction Steps
In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and N-(2-methoxyethyl)methylamine were converted to yield {3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-(2-methoxy-ethyl)-methyl-amine as colorless oil, MS: 374 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07173043B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-c2a85a057a0145849588107f3b80de19 |
| Source note | uspto-grants-2007_02 |