N-(2-Methoxyethyl)ethylamine → HCID 22314022, compound

HRID 347176Notes

Reaction equation

HRID 347176 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)=[CH:12][S:11][C:10]=2[CH:21]=1.[CH3:22][O:23][CH2:24][CH2:25][NH:26][CH2:27][CH3:28]>>[CH2:27]([N:26]([CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)=[CH:12][S:11][C:10]=2[CH:21]=1)[CH2:25][CH2:24][O:23][CH3:22])[CH3:28]

Participants

3

Reactant 2

HCID 546877N-(2-Methoxyethyl)ethylamineHCID 223140346-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene

Product 1

HCID 22314022HCID 22314022, compound

Procedure

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and N-(2-methoxyethyl)ethylamine were converted to yield Ethyl-{3-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-(2-methoxy-ethyl)-amine as colorless oil, MS: 388 (MH+).

Sources & evidence

ORD record
ord-5eadf52a43964ce5a1d61a985a4ceed4
Source dataset
uspto-grants-2007_02
Patent number
US07173043B2

Reaction notes

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