Diethanolamine → 2-[{4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol

Participants

Role	Name	HCID	Charge
Reactant	Diethanolamine	HCID 8113	—
Reactant	6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene	HCID 22313938	—
Product	2-[{4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol	HCID 22314105	—

Reaction Steps

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and diethanolamine were converted to yield 2-[{4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol as white semisolid, MS: 404 (MH+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07173043B2
Source dataset	uspto-grants-2007_02
ORD ID	ord-cf561f57edc84a5d8e0851d500965495
Source note	uspto-grants-2007_02